Exercise against hunger

Exercise is an unusual suspect when comes to reducing hunger. But it’s there, happily and effectively negating those hunger hormones with the tenacity of a woodpecker.

TLDR: Hunger can effectively be reduced through exercise. It is thereby an effective method to counteract the hunger-hormone ghrelin and to disrupt eating habits.

Imagine you try fasting and lunch-time comes about. Your stomach growls and the urge to peek into the fridge becomes almost overwhelming. Going for a run will probably be the last thing on your wish list in that moment. But in many if not all instances, it is among the best things you can do. Because…

So follow us on this nosy exploration of how…

Exercise affects hunger

The basics

When scientists investigated the eating-habits of exercising folk, like athletes, it turned out that exercise does not only not increase hunger, even at high intensities, but, and imagine this article’s autor’s surprise, can also reduce appetite, more efficiently than a delicious set of cookies on a plate [Thompson 1988, King 1995, King 1996, King 1997, Westerterp-Plantenga 1997, Lluch 1998, Blundell 1999, Vatansever-Ozen 2011].
Uff, I better do some push ups.

Even vigorous (“sweatily screaming for mercy”) exercise has at least temporarily a negative effect on hunger [King 1994, King 1995, Westerterp-Plantenga 1997, Lluch 1998, Bellisle 1999, Tsofliou 2003].

It is a baffling phenomenon and surely has some evolutionary purpose behind it. Feeling hungry and wanting to just snack on a couch might have been detrimental for food finding or hunting purposes, back when our meals were roaming the great savannas.

How does exercise do?

The story of exercise and hunger has 3 parts: One direct, leading us into the labyrinth of the intestines up to the brain, a second of blood and energy and a third of alarms and habits.

A mechanism that bridges the gut to the brain

Exercise makes us sweat, ache and sometimes scream, but did you know that it also builds bridges? In fact, it triggers the release of a whole sack of building blocks in the gut that activate all sorts of spots on the central nervous system. These building blocks, that put any minecraft enthusiast to shame and are excreted by something as simple as a jump up the stairs, are:

  • GLP-1 [O’Connor 1995, O’Connor 2006, Martins 2007]
  • CCK [Shillabeer 1987, Bailey 2001, Sliwowski 2001]
  • PYY [Bartolome 2002, Batterham 2002, Batterham 2003, Martins 2007]
  • PP [Hilsted 1980, Sullivan 1984, O’Connor 1995, Sliwowski 2001 ,Martins 2007]

One of the original functions of PYY, CCK and GLP-1 is the inhibition of gastric emptying [Liddle 1995, Liu 1996, Gautier 2008]. It makes sense that we shouldn’t have to worry about potty brakes when we are running for our lives or hunting after our breakfast.

But that is only one of the many effects of these hormones. The other important one is their anorectic properties [Shillabeer 1987, Batterham 2002, Batterham 2003, Gautier 2008]. Translated to the common tongue anorectic means “they reduce appetite” which in turn means:

Exercise triggers the release of gastrointestinal hormones that reduce hunger.

A mechanism of blood and energy

Then there is the second way exercise influences our foody-cravings. This time, we follow the spike of adrenaline that accompanies any good training session …right? Riiiiight!?.
Of course.

Similar to how caffeine affects adrenaline, exercise too can spray it around like an over-enthusiastic firefighter while screaming “Bloody murder!” through our body’s corridors [Sullivan 1984].

The effects of adrenaline on hunger are well documented and show that adrenaline has a strong negative effect on our appetite [Russek 1980]. Similar to how caffeine does it with the glycogen sparing effect, exercise might work similarly due to the activation of fat burning aka. lipolysis [Ryu 2001].

Exercise reduces hunger through the release of adrenaline.

A mechanism of alarms and habits

Have you ever stood in front the fridge, pondering what to eat? Imagine – and we hope you ever only have to imagine such a scenario – that you are suddenly attacked by a huge bird. Food would probably be again the last thing on your mind.

The stress, or fight or flight response our body falls back on when under threat is triggered by our central nervous system, but the message is carried by hormones such as cortisol or again adrenaline [Sullivan 1984, Hill 2008].

Like in large organizations, the majority of our body is blissfully ignorant to events like the comings and goings of giant birds. Which means every time our dear cells sniff the rise of stress hormones they respond accordingly and the only way they know how. Exercise hijacks this response and reduces through the release of stress hormones our baseline food intake [Murphy 2006].

We will take a more in depth look into these kinds of mechanisms with future guides, but can be happy to know that if applied right, this effect can be used to disrupt the habitual hunger trigger.

Exercise reduces hunger through a stress response.

Outro

Especially at medium to high levels, exercise is an effective way to reduce hunger and could be a viable way to overcome the hunger pangs. So instead of heading to out to grab a bite, consider that run.

Sources

KeyCitation
Bailey 2001Bailey, D. M., Davies, B., Castell, L. M., Newsholme, E. A., & Calam, J. (2001). Physical exercise and normobaric hypoxia: independent modulators of peripheral cholecystokinin metabolism in man. Journal of Applied Physiology90(1), 105-113.
Bartolome 2002Bartolomé, M. A., Borque, M., Martinez-Sarmiento, J., Aparicio, E., Hernández, C., Cabrerizo, L., & Fernandez-Represa, J. A. (2002). Peptide YY secretion in morbidly obese patients before and after vertical banded gastroplasty. Obesity surgery12(3), 324-327.
Batterham 2002Batterham, R. L., Cowley, M. A., Small, C. J., Herzog, H., Cohen, M. A., Dakin, C. L., … & Bloom, S. R. (2002). Gut hormone PYY3-36 physiologically inhibits food intake. Nature418(6898), 650-654.
Batterham 2003Batterham, R. L., Cohen, M. A., Ellis, S. M., Le Roux, C. W., Withers, D. J., Frost, G. S., … & Bloom, S. R. (2003). Inhibition of food intake in obese subjects by peptide YY3–36. New England Journal of Medicine349(10), 941-948.
Bellisle 1999Bellisle, F. (1999). Food choice, appetite and physical activity. Public health nutrition2(3a), 357-361.
Blundell 1999Blundell, J. E., & King, N. A. (1999). Physical activity and regulation of food intake: current evidence. Medicine and science in sports and exercise31(11 Suppl), S573-83.
Gautier 2008Gautier, J. F., Choukem, S. P., & Girard, J. (2008). Physiology of incretins (GIP and GLP-1) and abnormalities in type 2 diabetes. Diabetes & metabolism34, S65-S72.
Hill 2008Hill, E. E., Zack, E., Battaglini, C., Viru, M., Viru, A., & Hackney, A. C. (2008). Exercise and circulating cortisol levels: the intensity threshold effect. Journal of endocrinological investigation31, 587-591.
Hilsted 1980Hilsted, J., Galbo, H., Sonne, B., Schwartz, T., Fahrenkrug, J., de Muckadell, O. B., … & Tronier, B. (1980). Gastroenteropancreatic hormonal changes during exercise. American Journal of Physiology-Gastrointestinal and Liver Physiology239(3), G136-G140.
King 1994King, N. A., Burley, V. J., & Blundell, J. E. (1994). Exercise-induced suppression of appetite: effects on food intake and implications for energy balance. European journal of clinical nutrition48(10), 715-724.
King 1995King, N. A., & Blundell, J. E. (1995). High-fat foods overcome the energy expenditure induced by high-intensity cycling or running. European journal of clinical nutrition49(2), 114-123.
King 1996King, N. A., Snell, L., Smith, R. D., & Blundell, J. E. (1996). Effects of short-term exercise on appetite responses in unrestrained females. European journal of clinical nutrition50(10), 663-667.
King 1997King, N. A., Lluch, A., Stubbs, R. J., & Blundell, J. E. (1997). High dose exercise does not increase hunger or energy intake in free living males. European journal of clinical nutrition51(7), 478-483.
Liddle 1995Liddle, R. A. (1995). Regulation of cholecystokinin secretion by intraluminal releasing factors. American Journal of Physiology-Gastrointestinal and Liver Physiology269(3), G319-G327.
Liu 1996Liu, C. D., Aloia, T., Adrian, T. E., Newton, T. R., Bilchik, A. J., Zinner, M. J., … & Mcfadden, D. W. (1996). Peptide YY: a potential proabsorptive hormone for the treatment of malabsorptive disorders. The American Surgeon62(3), 232-236.
Lluch 1998Lluch, A., King, N. A., & Blundell, J. E. (1998). Exercise in dietary restrained women: no effect on energy intake but change in hedonic ratings. European journal of clinical nutrition52(4), 300-307.
Martins 2007Martins, C., Morgan, L. M., Bloom, S. R., & Robertson, M. D. (2007). Effects of exercise on gut peptides, energy intake and appetite. Journal of Endocrinology193(2), 251-258.
Murphy 2006Murphy, K. G., & Bloom, S. R. (2006). Gut hormones and the regulation of energy homeostasis. Nature444(7121), 854-859.
O’Connor 1995O’connor, A. M., Johnston, C. F., Buchanan, K. D., Boreham, C., Trinick, T. R., & Riddoch, C. J. (1995). Circulating gastrointestinal hormone changes in marathon running. International journal of sports medicine16(05), 283-287.
Russek 1980Russek, M., & Racotta, R. (1980). A Possible Role of Adrenaline and Glucagon in the Control of Food Intake1. In Comparative Aspects of Neuroendocrine Control of Behavior (Vol. 6, pp. 120-137). Karger Publishers.
Ryu 2001Ryu, S., Choi, S. K., JoUNG, S. S., Suh, H., Cha, Y. S., Lee, S., & Lim, K. (2001). Caffeine as a lipolytic food component increases endurance performance in rats and athletes. Journal of nutritional science and vitaminology47(2), 139-146.
Shillabeer 1987Shillabeer, G., & Davison, J. S. (1987). Proglumide, a cholecystokinin antagonist, increases gastric emptying in rats. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology252(2), R353-R360.
Sliwowski 2001Sliwowski, Z., Lorens, K., Konturek, S. J., Bielanski, W., & Zoladz, J. A. (2001). Leptin, gastrointestinal and stress hormones in response to exercise in fasted or fed subjects and before or after blood donation. Journal of physiology and pharmacology52(1).
Sullivan 1984Sullivan, S. N., Champion, M. C., Christofides, N. D., Adrian, T. E., & Bloom, S. R. (1984). Gastrointestinal regulatory peptide responses in long-distance runners. The Physician and Sportsmedicine12(7), 77-82.
Thompson 1988Thompson, D. A., Wolfe, L. A., & Eikelboom, R. (1988). Acute effects of exercise intensity on appetite in young men. Medicine and science in sports and exercise20(3), 222-227.
Tsofliou 2003Tsofliou, F., Pitsiladis, Y. P., Malkova, D., Wallace, A. M., & Lean, M. E. J. (2003). Moderate physical activity permits acute coupling between serum leptin and appetite–satiety measures in obese women. International journal of obesity27(11), 1332-1339.
Vatansever-Ozen 2011Vatansever-Ozen, S., Tiryaki-Sonmez, G., Bugdayci, G., & Ozen, G. (2011). The effects of exercise on food intake and hunger: Relationship with acylated ghrelin and leptin. Journal of sports science & medicine, 10(2), 283.
Westerterp-Plantenga 1997Westerterp-Plantenga, M. S., Verwegen, C. R., IJedema, M. J., Wijckmans, N. E., & Saris, W. H. (1997). Acute effects of exercise or sauna on appetite in obese and nonobese men. Physiology & behavior62(6), 1345-1354.

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